viagra triangle chicago illinois Lupus nephritis. Low-dose intravenous cyclophosphamide was more efficacious and safer than high-dose intravenous cyclophosphamide for the treatment of severe lupus nephritis. Crd commentary the review question was stated. Inclusion criteria were defined but not followed; inclusion criteria stated that regimes of intravenous cyclophosphamide were eligible, but one trial used oral cyclophosphamide and was included in the meta-analyses. Only two databases plus references were searched. No attempts were made to minimise publication bias. generic viagra online cheap generic viagra buy viagra online viagra without a doctor prescription buy cheap viagra viagra without a doctor prescription cheap generic viagra cheap viagra online It was not clear if any language restrictions were applied. The potential for publication bias was assessed but, as the authors stated, tests were of limited value given the small number of trials. Review methods were not reported, so the risk of reviewer errors and/or bias affecting study selection, assessment of study quality and data extraction was unclear. Trial quality was assessed, but only aggregate scores were reported; most trials appeared to be of low quality. Little information was provided about participants. Despite the authors stating that outcomes can differ across ethnic groups, ethnicity was only mentioned for two trials. Methods used for meta-analyses were generally appropriate; heterogeneity was assessed. The limited search, lack of reporting of review methods and evidence based on a few small trials of limited quality mean that the authors’ conclusions should be interpreted with caution. Implications of the review for practice and research the authors did not state any implications for practice or research. Funding ministry of health, welfare and family affairs (republic of korea), korea healthcare technology r and d project, grant number a080588. Bibliographic details lee yh, woo jh, choi sj, ji jd, song gg. Induction and maintenance therapy for lupus nephritis: a systematic review and meta-analysis. Lupus 2010; 19(6): 703-710 pubmedid 20064907 original paper url indexing status subject indexing assigned by nlm mesh azathioprine /adverse effects /therapeutic use; bias (epidemiology); cyclophosphamide /adverse effects /therapeutic use; humans; immunosuppressive agents /adverse.